Candida Research Today is a free monthly online journal that collates and summarizes the latest research about Candida, including details on thrush infections, yeast, diet, treatment, symptoms.

A fungicidal monoclonal antibody protects against murine invasive candidiasis.

Sevilla MJ, Robledo B, Rementeria A, Moragues MD, Pontón J

Departamento de Inmunología, Microbiología y Parasitología, Facultad de Ciencia y Tecnología, Universidad del País Vasco, Apartado 644, E-48080 Bilbao, Vizcaya, Spain. mariajesus.sevilla@ehu.es

Mice infected by Candida albicans and treated with monoclonal antibody C7 survived longer than saline-treated animals. A prozone-like effect was observed. The in vitro candidacidal activity of macrophages was strongly enhanced when C. albicans was opsonized by C7 and complete murine serum was present.

Published 19 April 2006 in Infect Immun, 74(5): 3042-5.
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