Candida Research Today is a free monthly online journal that collates and summarizes the latest research about Candida, including details on thrush infections, yeast, diet, treatment, symptoms.

Killed Candida albicans yeasts and hyphae inhibit gamma interferon release by murine natural killer cells.

Murciano C, Villamón E, O'Connor JE, Gozalbo D, Gil ML

Departamento de Microbiología y Ecología, Facultad de Ciencias Biológicas, Edificio de Investigación, C/ Dr. Moliner 50, 46100 Burjasot, Valencia, Spain.

Killed yeasts and hyphae of Candida albicans inhibit gamma interferon secretion by highly purified murine NK cells in response to the Toll-like receptor ligands lipopolysaccharide and zymosan. This effect, which is also observed in the presence of NK-activating cytokines (interleukin-2 [IL-2], IL-12, and IL-15), may represent a novel mechanism of immune evasion that contributes to the virulence of C. albicans.

Published 23 January 2006 in Infect Immun, 74(2): 1403-6.
Full-text of this article is available online (may require subscription).

© 2004-2008 Candida Research Today. All Rights Reserved.