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Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis.

Philip A, Odabasi Z, Matiuzzi G, Paetznick VL, Tan SW, Warmington J, Rex JH, Ostrosky-Zeichner L

Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas-Houston Medical School, 77030, USA.

Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.

Published 7 September 2005 in J Clin Microbiol, 43(9): 4834-5.
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