Candida Research Today is a free monthly online journal that collates and summarizes the latest research about Candida, including details on thrush infections, yeast, diet, treatment, symptoms.

In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata.

Oliveira ER, Fothergill AW, Kirkpatrick WR, Coco BJ, Patterson TF, Redding SW

Department of General Dentistry, University of Texas Health Science Center at San Antonio, Mail Code 7914, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. oliveirae@uthscsa.edu

Combinations of caspofungin and posaconazole were evaluated by fractional inhibitory concentration index against 119 Candida glabrata isolates. Synergy was seen in 18% of all isolates and in 4% of fluconazole-resistant isolates at 48 h without evidence of antagonism. This antifungal combination may have utility against this organism.

Published 28 July 2005 in Antimicrob Agents Chemother, 49(8): 3544-5.
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