Candida Research Today is a free monthly online journal that collates and summarizes the latest research about Candida, including details on thrush infections, yeast, diet, treatment, symptoms.

High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa.

Nie Y, Xu Y, Qing Mu X, Tang Y, Jiang J, Hao Sun Z

Key Laboratory of Industrial Biotechnology of Ministry of Education & School of Biotechnology, Southern Yangtze University, 214036, Wuxi, P.R. China.

Whole cells of Candida rugosa catalyzed the conversion of (R)-2-octanol from the corresponding racemate with the optical purity of 97% e.e. and yield of 92% in 10 h. The product was formed through a stereoinversion involving enantioselective oxidation and asymmetric reduction with 2-octanone as the intermediate.

Published 1 February 2005 in Biotechnol Lett, 27(1): 23-6.
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