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Effect of inoculum size on detection of Candida growth by the BACTEC 9240 automated blood culture system using aerobic and anaerobic media.

George BJ, Horvath LL, Hospenthal DR

Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Simulated candidemia was produced with 20 Candida isolates at three inoculum sizes (100, 10, and 1 CFU/ml of blood). Growth detection was better with larger inocula. The time to growth detection was shorter with larger inocula. Inoculum size does effect Candida growth detection and time to detection in BACTEC 9240 automated systems.

Published 6 January 2005 in J Clin Microbiol, 43(1): 433-5.
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